American Serenade
American Cruise Lines
American Serenade Sailing Dates and Sailing Calendar
For more information, prices, and detailed day-by-day American Serenade itineraries, please click one of the American Serenade sailing dates below.
Sail Date |
Itinerary Name and Ports |
Duration |
Save to Favorites |
Priced From(per person) |
|---|---|---|---|---|
|
Jun 12, 2026
(Friday)
|
22 Night Complete Mississippi River Experience Cruise and Land Tour
From New Orleans, Louisiana to St Paul, Minnesota Ports: New Orleans, River Cruising, Oak Alley, Baton Rouge, St Francisville, Natchez, Vicksburg, Greenville, Tunica, Memphis, Cruising the Mississippi River, Cape Girardeau, River Cruising, St Louis, River Cruising, Hannibal, River Cruising, Muscatine, Dubuque, River Cruising, Winona, Red Wing, St Paul |
22 Nights
|
  Add to Favorites |
$15,890
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Jul 3, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Paul, Minnesota to St Louis, Missouri Ports: St Paul, Red Wing, La Crosse, Cruising the Mississippi River, Dubuque, Davenport Iowa, Hannibal, Alton Illinois, St Louis |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Jul 10, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Louis, Missouri to St Paul, Minnesota Ports: St Louis, Alton Illinois, Hannibal, Cruising the Mississippi River, Muscatine, Dubuque, Winona, Red Wing, St Paul 
|
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Jul 17, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Paul, Minnesota to St Louis, Missouri Ports: St Paul, Red Wing, La Crosse, Cruising the Mississippi River, Dubuque, Davenport Iowa, Hannibal, Alton Illinois, St Louis |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Jul 24, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Louis, Missouri to St Paul, Minnesota Ports: St Louis, Alton Illinois, Hannibal, Cruising the Mississippi River, Muscatine, Dubuque, Winona, Red Wing, St Paul |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Jul 31, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Paul, Minnesota to St Louis, Missouri Ports: St Paul, Red Wing, La Crosse, Cruising the Mississippi River, Dubuque, Davenport Iowa, Hannibal, Alton Illinois, St Louis |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Aug 7, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Louis, Missouri to St Paul, Minnesota Ports: St Louis, Alton Illinois, Hannibal, Cruising the Mississippi River, Muscatine, Dubuque, Winona, Red Wing, St Paul |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Aug 14, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Paul, Minnesota to St Louis, Missouri Ports: St Paul, Red Wing, La Crosse, Cruising the Mississippi River, Dubuque, Davenport Iowa, Hannibal, Alton Illinois, St Louis |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Aug 21, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Louis, Missouri to St Paul, Minnesota Ports: St Louis, Alton Illinois, Hannibal, Cruising the Mississippi River, Muscatine, Dubuque, Winona, Red Wing, St Paul |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Aug 28, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Paul, Minnesota to St Louis, Missouri Ports: St Paul, Red Wing, La Crosse, Cruising the Mississippi River, Dubuque, Davenport Iowa, Hannibal, Alton Illinois, St Louis |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Sep 4, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Louis, Missouri to St Paul, Minnesota Ports: St Louis, Alton Illinois, Hannibal, Cruising the Mississippi River, Muscatine, Dubuque, Winona, Red Wing, St Paul |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Sep 11, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Paul, Minnesota to St Louis, Missouri Ports: St Paul, Red Wing, La Crosse, Cruising the Mississippi River, Dubuque, Davenport Iowa, Hannibal, Alton Illinois, St Louis |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Sep 18, 2026
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Louis, Missouri to St Paul, Minnesota Ports: St Louis, Alton Illinois, Hannibal, Cruising the Mississippi River, Muscatine, Dubuque, Winona, Red Wing, St Paul |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Sep 25, 2026
(Friday)
|
15 Night Grand Heartland Cruise and Land Tour
From St Paul, Minnesota to New Orleans, Louisiana Ports: St Paul, Cruising the Mississippi River, La Crosse, Dubuque, Davenport Iowa, River Cruising, Hannibal, River Cruising, St Louis, Memphis, Tunica, Cruising the Mississippi River, Vicksburg, Natchez, Baton Rouge, New Orleans |
15 Nights
|
Add to Favorites |
$12,620
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Oct 29, 2026
(Thursday)
|
11 Night Mississippi Explorer Cruise and Land Tour
From New Orleans, Louisiana to Memphis, Tennessee Ports: New Orleans, River Cruising, Oak Alley, Baton Rouge, St Francisville, Natchez, Vicksburg, Cruising the Mississippi River, Terrene Landing, Tunica, Memphis |
11 Nights
|
Add to Favorites |
$7,770
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Nov 25, 2026
(Wednesday)
|
7 Night Historic Mississippi River Cruise and Land Tour
From New Orleans, Louisiana to New Orleans, Louisiana Ports: New Orleans, Cruising the Mississippi River, Houmas House, Oak Alley, Baton Rouge, Natchez, Vicksburg, Natchez, St Francisville, New Orleans 
|
7 Nights
|
Add to Favorites |
Call
For Price Interior (double occupancy) Learn More |
|
Dec 1, 2026
(Tuesday)
|
7 Night Historic Mississippi River Cruise and Land Tour
From New Orleans, Louisiana to New Orleans, Louisiana Ports: New Orleans, Cruising the Mississippi River, Houmas House, Oak Alley, Baton Rouge, Natchez, Vicksburg, Natchez, St Francisville, New Orleans
|
7 Nights
|
Add to Favorites |
Call
For Price Interior (double occupancy) Learn More |
|
Jun 4, 2027
(Friday) |
8 Night Lower Mississippi Cruise
From Memphis, Tennessee to New Orleans, Louisiana Ports: Memphis, Cruising the Mississippi River, Terrene Landing, Vicksburg, Natchez, St Francisville, Cruising the Mississippi River, Oak Alley, New Orleans |
8 Nights
|
Add to Favorites |
Call
For Price Interior (double occupancy) Learn More |
|
Jun 11, 2027
(Friday)
|
22 Night Complete Mississippi River Experience Cruise and Land Tour
From New Orleans, Louisiana to St Paul, Minnesota Ports: New Orleans, River Cruising, Oak Alley, Baton Rouge, St Francisville, Natchez, Vicksburg, Greenville, Tunica, Memphis, Cruising the Mississippi River, Cape Girardeau, River Cruising, St Louis, River Cruising, Hannibal, River Cruising, Muscatine, Dubuque, River Cruising, Winona, Red Wing, St Paul |
22 Nights
|
Add to Favorites |
$15,890
Balcony (double occupancy) Includes taxes & feesLearn More |
|
Jul 2, 2027
(Friday)
|
8 Night Upper Mississippi Cruise and Land Tour
From St Paul, Minnesota to St Louis, Missouri Ports: St Paul, Red Wing, La Crosse, Cruising the Mississippi River, Dubuque, Davenport Iowa, Hannibal, Alton Illinois, St Louis |
8 Nights
|
Add to Favorites |
$5,635
Balcony (double occupancy) Includes taxes & feesLearn More |
